Selection maintaining protein stability at equilibrium
نویسندگان
چکیده
منابع مشابه
Selection maintaining protein stability at equilibrium.
The common understanding of protein evolution has been that neutral mutations are fixed by random drift, and a proportion of neutral mutations depending on the strength of structural and functional constraints primarily determines evolutionary rate. Recently it was indicated that fitness costs due to misfolded proteins are a determinant of evolutionary rate and selection originating in protein ...
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ANY authors (BENNETT 1958; EDWARDS 1961 ; HALDANE 1923-26; HALDANE Mand JAYAKAR 1964; KIMURA 1960; MANDEL 1959; SHAW 1959; and SPROTT 1957) have discussed the behaviour of a sex-linked locus under natural selection. The discussion included in these papers has been entirely confined to the investigation of the existence and stability of nondegenerate equilibria. This is an important problem, but...
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In this paper we use a non cooperative equilibrium selection approach as a notion of stability in link formation games. Specifically, we follow the global games approach first introduced by Carlsson and van Damme (1993), to study the robustness of the set of Nash equilibria for a class of link formation games in strategic form with supermodular payoff functions. Interestingly, the equilibrium s...
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ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2016
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2015.12.001